| Planet Labs | São Francisco | 28 de dezembro de 2010 |
| Plantronics | Santa Cruz | 1961 |
| Plug Power | Latham, Slingerlands | 1997 |
| PNC Financial Services | One PNC Plaza | 1982 |
| Polaris Industries | Medina | 1954 |
| PPG Industries | Pittsburgh | 1883 |
| Procter & Gamble | Ohio, Cincinnati | 31 de outubro de 1837 |
| Publix | Lakeland | 27 de dezembro de 1921 |
| Qualcomm | San Diego | julho 1985 |
| Qualtrics | Provo | 2002 |
| Quiksilver | Huntington Beach | 1969 |
| Ralph Lauren (marca) | Nova Iorque | 1967 |
| Rayovac | Middleton | 1906 |
| Raytheon | Waltham | 7 de julho de 1922 |
| Red Robin | Greenwood Village | 1940 |
| Revlon | Nova Iorque | 1932 |
| Reynolds American | Winston-Salem | 2004 |
| Robinhood | Palo Alto | 2013 |
| Rocky Mountain Chocolate Factory | Durango | 1981 |
| Ruby Tuesday (restaurante) | — | 1972 |
| S&P Global | Rockefeller Center, Nova Iorque | — |
| Safeway | Pleasanton | 1915 |
| Sanmina-SCI | São José | 1980 |
| Schlumberger | Houston | 1926 |
| Sealy Corporation | Trinity | 1881 |
| Sears | Hoffman Estates | 1892 |
| SFX Entertainment | Burbank | 10 de março de 2014 |
| Silicon Laboratories | Austin | 1996 |
| Silvergate Capital | La Jolla | 1988 |
| Sirius XM Radio | Nova Iorque | 29 de julho de 2008 |
| Six Flags | Arlington | 1961 |
| Skullcandy | Park City | 2003 |
| Skydance Corporation | Los Angeles, One Astor Plaza | 7 de agosto de 2025 |
| Smith & Wesson | Springfield | 1852 |
| Snap Inc. | Santa Mônica, Venice | 16 de setembro de 2011 |
| Snap-on | Kenosha | 1920 |
| SolarWinds | Austin | 1999 |
| Southern Company | Atlanta | 1945 |
| SpaceX | Starbase | 14 de março de 2002 |
| Speedway Motorsports | Concord | 1959 |
| Spirit Airlines | Dania Beach | 1983 |
| Sprint Nextel | Overland Park | 1899 |
| Stanley Black & Decker | New Britain | 1843 |
| Staples Inc. | Framingham | 1986 |
| State Street Corporation | Boston | 1792 |
| Stepan Company | Northfield | 1932 |
| Sun Microsystems | Santa Clara | 24 de fevereiro de 1982 |
| SunPower | São José | 1985 |