| Abbott Motor Company | Detroit | 1909 |
| Baker Motor Vehicle | Cleveland | 1899 |
| Cadillac | Detroit | 1902 |
| Chevrolet | Detroit | 3 de novembro de 1911 |
| Coda Automotive | Los Angeles | 2009 |
| Crosley | Cincinnati | 1937 |
| DeLorean Motor Company | Detroit | 24 de outubro de 1975 |
| Detroit Diesel | Detroit | 1938 |
| Dodge | Dodge Building | 14 de dezembro de 1900 |
| Durant Motors | Lansing | 1921 |
| Excalibur | Milwaukee | 1963 |
| Ford Motor Company | Dearborn | 16 de junho de 1903 |
| General Motors | Detroit | 16 de setembro de 1908 |
| Google driverless car | Mountain View | 13 de dezembro de 2016 |
| Hupmobile | Detroit | 1909 |
| International Harvester | Chicago | 1902 |
| Kaiser Jeep | Toledo | 1953 |
| Kaiser Motors | Ypsilanti | 1945 |
| Local Motors | Phoenix | 2007 |
| Lucid Motors | Newark | 2007 |
| Marquette | — | 1909 |
| Mosler Automotive | Riviera Beach | 1985 |
| Panoz | Hoschton | 1989 |
| Peerless | Cleveland | 1900 |
| Pierce-Arrow | Buffalo | 1870 |
| Polaris Industries | Medina | 1954 |
| Pope Manufacturing Company | Hartford | 1876 |
| Ram Trucks | Auburn Hills | 2010 |
| Saleen | Corona | 1983 |
| Stanley Motor Carriage Company | Newton | 1902 |
| Studebaker | South Bend | 1852 |
| Studebaker-Packard Corporation | Detroit | 1954 |
| Vector Aeromotive | — | 1978 |
| Willys Overland | Toledo | 1908 |
| Winton Motor Carriage Company | Cleveland | 1897 |